Minor/Significance Unknown. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion), trouble urinating. Otherwise, call a poison control center right away. Coadministration of mild CYP3A4 inhibitors with midazolam intranasal may cause higher midazolam systemic exposure, which may prolong sedation. JAMA 274 (1995): 301, 32. Minor/Significance Unknown. Acetaminophen containing products: Not to exceed a cumulative dose of 3.25 g/day of acetaminophen; under supervision of healthcare professional, daily doses of up to 4 g/day may be used. Minor (1)acetaminophen increases effects of protamine by unknown mechanism. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Apalutamide induces UGT and may decrease systemic exposure of drugs that are UGT substrates. Minor/Significance Unknown. Enhanced metabolism incr levels of hepatotoxic metabolites. Ann Allergy 72 (1994): 285, 40. tetracaine, acetaminophen. Modify Therapy/Monitor Closely. Johnson GK, Tolman KG "Chronic liver disease and acetaminophen." Since that time, manufacturers and retailers of pediatric acetaminophen have voluntarily worked to change the amount of acetaminophen in these medicines to . Keep all medications away from children and pets. Controlled studies in pregnant women show no evidence of fetal risk. Enhanced metabolism incr levels of hepatotoxic metabolites. ethosuximide decreases levels of acetaminophen by increasing metabolism. acetaminophen, bupivacaine implant. Minor (1)oxybutynin topical decreases levels of acetaminophen by unspecified interaction mechanism. Take your next dose at the regular time. Use Caution/Monitor. People with liver problems and children should take less acetaminophen. Advil Pain Reliever and Fever Reducer, Ibuprofen 200mg for Pain Relief - 300 Count, Advil PM Pain Reliever and Nighttime Sleep Aid, Ibuprofen for Pain Relief and Diphenhydramine Citrate - 2 Count, Tylenol Infants Oral Suspension Liquid Medicine with Acetaminophen, Baby Fever Reducer & Pain Reliever for Minor Aches & Pains, Sore Throat, Headache & Toothache, Grape Flavor, 2 fl. do not take more than 6 gelcaps in 24 hours. Ask your doctor or pharmacist how much acetaminophen is safe to take.Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Take this medication by mouth with or without food or as directed by your doctor. Smilkstein MJ, Douglas Dr, Daya MR "Acetaminophen poisoning and liver function." acetazolamide decreases levels of acetaminophen by increasing metabolism. An overdose of acetaminophen can be fatal. Formulated for fast-acting muscle pain relief including joint, knee and other minor aches and pains. Hartleb M "Do thyroid hormones promote hepatotoxicity to acetaminophen?" However, since some people may develop serious health issues such as liver . Minor/Significance Unknown. "Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial." Drug interactions may change how your medications work or increase your risk for serious side effects. Use Caution/Monitor. This document does not contain all possible drug interactions. Leung R, Plomley R, Czarny D "Paracetamol anaphylaxis." Enhanced metabolism incr levels of hepatotoxic metabolites. Arch Intern Med 145 (1985): 2019-23, 7. No effects on acetaminophen Cmax and Tmax were observed when acetaminophen was administered 1 hr before lixisenatide. Use Caution/Monitor. Monitor Closely (1)acetaminophen will increase the level or effect of lemborexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Lancet 342 (1993): 869, 22. WARNINGS Liver warning: This product contains acetaminophen. What medications cause liver enzymes to be elevated? Use Caution/Monitor. Increased flibanserin adverse effects may occur if coadministered with multiple weak CYP3A4 inhibitors. Do not use a household spoon because you may not get the correct dose. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdHlsZW5vbC1hY2V0YW1pbm9waGVuLTM0MzM0Ng==. Whitcomb DC, Block GD "Association of acetaminopphen hepatotoxicity with fasting and ethanol use." )If you are giving acetaminophen to a child, be sure you use a product that is meant for children. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor/Significance Unknown. To avoid potential interaction, give acetaminophen at least 1 hour before or 4 hours after exenatide injection. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Vitols S "Paracetamol hepatotoxicity at therapeutic doses." Minor/Significance Unknown. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Block R, Jankowski JA, Lacoux P, Pennington CR "Does hypothermia protect against the development of hepatitis in paracetamol overdose?" Antihistamines can also be used to help relieve allergy or cold symptoms such as watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. oz, Tylenol Cold Max Daytime Non-Drowsy Cold and Flu Relief, Acetaminophen, 24 ct, Get Fast Pain Relief & Sleep the Whole Night, Doctor-recommended relief for minor aches & pains. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor (1)levetiracetam decreases levels of acetaminophen by increasing metabolism. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Use Caution/Monitor. Applies only to oral form of both agents. Brotodihardjo AE, Batey RG, Farrell GC, Byth K "Hepatotoxicity from paracetamol self-poisoning in Western Sydney: a continuing challenge." The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. It is important to follow the directed dose and wait the correct amount of time between doses to avoid harmful side effects. Time is fleeting. Some side effects may not be reported. Minor/Significance Unknown. Guccione JL, Zemtsov A, Cobos E, Neldner KH "Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k." Arch Dermatol 129 (1993): 1267-9, 47. Minor (1)acetaminophen increases effects of enoxaparin by unknown mechanism. Minor (1)fosphenytoin decreases levels of acetaminophen by increasing metabolism. Minor/Significance Unknown. This site is published by McNeil Consumer Healthcare, division of Johnson & Johnson Inc. which is solely responsible for its content. Minor (1)disulfiram will increase the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. Enhanced metabolism incr levels of hepatotoxic metabolites. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Avoid or Use Alternate Drug. Minor (1)cholestyramine decreases levels of acetaminophen by inhibition of GI absorption. Each pain relief tablet contains 650 mg of acetaminophen, an effective muscle pain reliever. Use these dosage charts for infants and children under 12 years old: Common (1% to 10%): Increased aspartate aminotransferase, Rare (less than 0.1%): Increased hepatic transaminases, Frequency not reported: Liver failure[Ref], Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%), Common (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomen, Postmarketing reports: Anaphylaxis, hypersensitivity reactions[Ref], Common (1% to 10%): Anemia, postoperative hemorrhage, Very rare (less than 0.01%): Thrombocytopenia, leucopenia, neutropenia[Ref], Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, Very rare (less than 0.01%): Pemphigoid reaction, pustular rash, Lyell syndrome[Ref], Common (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing[Ref], Common (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain[Ref], Common (1% to 10%): Hypokalemia, hyperglycemia[Ref], Common (1% to 10%): Muscle spasms, trismus, Common (1% to 10%): Infusion site pain, injection site reactions, Paracetamol, Ofirmev, Arthritis Pain Relief, Mapap, +32 more, 1. Minor/Significance Unknown. Minor/Significance Unknown. South Med J 81 (1988): 1163-6, 11. Minor/Significance Unknown. MISSED DOSE: If you are taking this medication on a regular schedule and miss a dose, take it as soon as you remember. 0 . 3 or more alcoholic drinks every day while using this product. ethanol will decrease the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. acetaminophen will increase the level or effect of ruxolitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Monitor Closely (1)acetaminophen increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Be extra cautious when taking 500 or 650 milligram pills. $10.88. exenatide injectable suspension will decrease the level or effect of acetaminophen by unspecified interaction mechanism. Van Diem L, Grilliat JP "Anaphylactic shock induced by paracetamol." Closely monitor for arrhythmias and events (eg, syncope, heart palpitations) since lonafarnib effect on QT interval is unknown. Do not take this product for fever more than 3 days unless directed by your doctor. Canada residents can call a provincial poison control center. May induce methemoglobinemia . Minor (2)ethanol will decrease the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. Minor/Significance Unknown. Minor/Significance Unknown. US residents can call their local poison control center at 1-800-222-1222. Thomas RH, Munro DD "Fixed drug eruption due to paracetamol." Kurtovic J, Riordan SM "Paracetamol-induced hepatotoxicity at recommended dosage." oz, Advil Pain Reliever And Fever Reducer, Pain Relief Medicine With Ibuprofen 200mg For Headache, Backache, Menstrual Pain And Joint Pain Relief - 50x2 Coated Tablets, Hyland's Naturals Arnica Montana 30x Tablets, Natural Relief of Bruises, Swelling & Muscle Soreness, Multi, 50 Count (Pack of 1), Advil Liqui-Gels Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Headache, Backache, Menstrual Pain and Joint Pain Relief - 80 Liquid Filled Capsules, Advil Liqui-Gels Pain Reliever And Fever Reducer, Pain Medicine For Adults With Ibuprofen 200mg For Headache, Backache, Menstrual Pain And Joint Pain Relief - 40 Liquid Filled Capsules, Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count, Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct, Tylenol Child & Adult Oral Suspension for Pain & Fever, Acetaminophen, Cherry, 8 fl. Consumer Healthcare, division of Johnson & Johnson Inc. Am J Med 96 (1994): 3-9, 24. If coadministration of lonafarnib (a sensitive CYP3A substrate) with weak CYP3A inhibitors is unavoidable, reduce to, or continue lonafarnib at starting dose. Can I take Tylenol while taking indomethacin and can these drugs be alternated every 3 hours? Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). metronidazole will increase the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. Minor/Significance Unknown. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Tylenol Extra-Strength (ie, 500 mg/tab or cap): Not to exceed 3 g/day (6 tabs or caps); under supervision of healthcare professional, daily doses of up to 4 g . aspirin, acetaminophen, ibuprofen, tramadol, cyclobenzaprine, Paracetamol, diclofenac, naproxen, oxycodone, Voltaren. Use Caution/Monitor. PRECAUTIONS: See also Warning section.Before taking acetaminophen, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug are: ketoconazole, levoketoconazole.This medication may interfere with certain laboratory tests, possibly causing false test results. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Minor (1)ethosuximide decreases levels of acetaminophen by increasing metabolism. Bonkovsky HL, Kane RE, Jones DP, Galinsky RE, Banner B "Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition - evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency." See drug monograph for specific dosage modification. acetaminophen will increase the level or effect of tazemetostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. find right dose on chart below. Hum Toxicol 7 (1988): 33-4, 10. BMJ 303 (1991): 1026-9, 13. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Minor/Significance Unknown. Minor/Significance Unknown. Advil (ibuprofen) & Tylenol (acetaminophen) together, is it safe? chew tablets completely before swallowing; do not swallow tablets whole repeat dose every 4 hours while symptoms last do not give more than 5 times in 24 hours *or as directed by a doctor What's the best sore throat medicine to use? This medication may interfere with certain medical/laboratory tests (such as urine 5-HIAA, allergy skin tests), possibly causing false test results. Minor/Significance Unknown. You may report side effects to Health Canada at 1-866-234-2345. Always carefully read and follow the label directions before using any over the counter medication. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor/Significance Unknown. Tylenol (Acetaminophen Capsules and Tablets), fever with or without chills (not present before treatment and not caused by the condition being treated), pain in the lower back and/or side (severe and/or sharp), sores, ulcers, or white spots on the lips or in the mouth, swelling, pain, or tenderness in the upper abdomen or stomach area. eltrombopag increases levels of acetaminophen by decreasing metabolism. * *The efficacy and safety of TYLENOL at 4000 mg/day are well established. Minor/Significance Unknown. Blood 109 (2007): 3608-9, 45. Enhanced metabolism increase levels of hepatotoxic metabolites. J Intern Med 253 (2003): 95-8, 6. Before taking this medication, tell your doctor or pharmacist if you are allergic to acetaminophen or antihistamines; or if you have any other allergies. Minor/Significance Unknown. acetaminophen increases effects of protamine by unknown mechanism. Use Caution/Monitor. GLP1 agonists delay gastric emptying, which may affect absorption of concomitantly administered oral medications. Lomitapide dose should not exceed 30 mg/day. Shriner K, Goetz MB "Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine." Other (see comment). Ask your doctor or pharmacist how much acetaminophen is safe to take. Halevi A, BenAmitai D, Garty BZ "Toxic epidermal necrolysis associated with acetaminophen ingestion." Swallow the tablets whole.For effervescent tablets, dissolve the dose in the recommended amount of water, then drink.Pain medications work best if they are used as the first signs of pain occur. To avoid potential interaction, give acetaminophen at least 1 hour before or 4 hours after exenatide injection. Minor (1)lamotrigine decreases levels of acetaminophen by increasing metabolism. Enhanced metabolism incr levels of hepatotoxic metabolites. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor/Significance Unknown. Enhanced metabolism incr levels of hepatotoxic metabolites. 3,000 mg in 24 hours Brand Names. Minor (1)metronidazole will increase the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. This content is intended solely as a general product and educational aid. Stick to recommended doses. rifampin decreases levels of acetaminophen by increasing metabolism. Enhanced metabolism incr levels of hepatotoxic metabolites. liraglutide decreases levels of acetaminophen by unspecified interaction mechanism. Minor/Significance Unknown. O'Dell JR, Zetterman RK, Burnett DA "Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic." 10/2023. Avoid or Use Alternate Drug. Use Caution/Monitor. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). N Engl J Med 333 (1995): 1118-27, 35. Store at room temperature away from light and moisture. Lee WM "Medical progress: drug-induced hepatotoxicity." Either increases toxicity of the other by Other (see comment). Minor/Significance Unknown. In young children, this drug may cause agitation and excitement instead of drowsiness. Is it safe to take acetaminophen every day? Always ask your health care professional for complete information about this product and your specific health needs. Reason: they are every 8-hour extended-release. Enhanced metabolism incr levels of hepatotoxic metabolites. Comment: Local anesthetics may increase the risk of developing methemoglobinemia when concurrently exposed to drugs that also cause methemoglobinemia. -. In the US - Call your doctor for medical advice about side effects. Johnson&Johnson Inc., 88 McNabb Street, Markham, ON L3R 5L2, 1-800-265-7323. levetiracetam decreases levels of acetaminophen by increasing metabolism. Extra Strength: 1000 mg PO q6-8hr PRN; not to exceed 3000 mg/day; under supervision of healthcare professional, daily doses of up to 4 g/day may be used: 2 capsules (1300 mg) PO q8hr PRN; not to exceed 3.9 g/day, Acetaminophen containing products: Not to exceed a cumulative dose of 3.25 g/day of acetaminophen; under supervision of healthcare professional, daily doses of up to 4 g/day may be used, Tylenol Extra-Strength (ie, 500 mg/tab or cap): Not to exceed 3 g/day (6 tabs or caps); under supervision of healthcare professional, daily doses of up to 4 g/day may be used, Neonates 28-31 weeks gestation: 10-15 mg/kg/dose PO q12hr prn; may administer an initial load of 20 mg/kg PO; not to exceed 40 mg/kg/day or 48 hr (consecutive) of maximum dose, Neonates 32-37 weeks gestation: 10-15 mg/kg/dose PO q8hr prn; may administer an initial load of 20 mg/kg PO; not to exceed 60 mg/kg/day or 48 hr (consecutive) of maximum dose, Neonates 0-9 days: 10-15 mg/kg/dose PO q6-8hr prn; may administer an initial load of 20 mg/kg PO; not to exceed 60 mg/kg/day; or 48 hr (consecutive) of maximum dose, Neonates 10-29 days: 10-15 mg/kg/dose PO q4-8hr prn; may administer an initial load of 20 mg/kg PO; not to exceed 90 mg/kg/day; or 48 hr (consecutive) of maximum dose, Infants: 10-15 mg/kg/dose PO q4-6hr prn; not to exceed 15 mg/kg/dose or 75 mg/kg/day, Children and adolescents <60 kg: 10-15 mg/kg/dose PO q4-6hr prn; not to exceed 15 mg/kg/dose or 1,000 mg/dose, whichever is less or 75 mg/kg/day or 4,000 mg/day, whichever is less, 6-12 years: 325-650 mg PO q4-6hr; not to exceed 1.625 g/day for not more than 5 days unless directed by healthcare provider, Regular strength: 325-650 mg q4-6hr; not to exceed 3.25 g/day; under supervision of healthcare professional, doses of up to 4 g/day may be used, Extra strength: 1000 mg q6hr; not to exceed 3 g/24hr; under supervision of healthcare professional, doses of up to 4 g/day may be used, Extended release: 1.3 g q8hr; not to exceed 3.9 g/24hr, levonorgestrel oral/ethinylestradiol/ferrous bisglycinate. WARNING: Taking too much acetaminophen may cause serious (possibly fatal) liver disease. For junior-strength suppositories that read 325 mg on the label: Give a dose: 2 suppositories every 4 to 6 hours Maximum dose: 6 doses in 24 hours Giving Medicine to Children Make sure you do not give your child more than one medicine that contains acetaminophen as an ingredient. Minor/Significance Unknown. Minor (1)valproic acid decreases levels of acetaminophen by increasing metabolism. Monitor Closely (1)acetaminophen will increase the level or effect of tazemetostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. More Buying Choices $11.39 (15 new offers) acetaminophen will increase the level or effect of flibanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Enhanced metabolism incr levels of hepatotoxic metabolites. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Take your next dose at the regular time. Enhanced metabolism incr levels of hepatotoxic metabolites. Your first offer is a $3 credit towards your next purchase of eligible Johnson&Johnson products on Amazon.ca. May induce methemoglobinemia . Pain medications work best if they are used as the first signs of pain occur. Skip Navigation. Minor/Significance Unknown. disulfiram will increase the level or effect of acetaminophen by affecting hepatic enzyme CYP2E1 metabolism. Minor (1)carbamazepine decreases levels of acetaminophen by increasing metabolism. Signs of poisoning include nausea, vomiting, fatigue, and abdominal pain. Adjust finererone dosage as needed. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Minor (1)acetazolamide decreases levels of acetaminophen by increasing metabolism. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Minor/Significance Unknown. Use Caution/Monitor. rifabutin decreases levels of acetaminophen by increasing metabolism. acetaminophen increases effects of heparin by unknown mechanism. Some dosage forms listed on this page may not apply to the brand name Tylenol. Adults . Third party trademarks contained herein are registered trademarks of their respective owners and not of McNeil Taking more increases your chance of harming your liver. Enhanced metabolism incr levels of hepatotoxic metabolites. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Tylenol PM Tablet side effects by likelihood and severity. These products do not cure or shorten the length of the common cold and may cause serious side effects. BMJ 306 (1993): 157-8, 23. Use Caution/Monitor. acetaminophen increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Enhanced metabolism incr levels of hepatotoxic metabolites. When calculating the maximum daily dose, consider all sources of acetaminophen, including OTC, and routes of administration not to exceed the maximum recommended daily dosing, GFR50 mL/min: No dosage adjustment necessary, Continuous renal replacement therapy: Administer q6hr, Use extreme caution; avoid use as much as possible; limit therapy to short-term use at doses not to exceed 2 g/day. Free shipping. Minor/Significance Unknown. The answer you entered for the CAPTCHA was not correct. Minor/Significance Unknown. To avoid potential interaction, give acetaminophen at least 1 hour before or 4 hours after exenatide injection. An overdose of acetaminophen can damage your liver or cause death. Data sources include IBM Watson Micromedex (updated 2 Dec 2022), Cerner Multum (updated 7 Dec 2022), ASHP (updated 11 Nov 2022) and others. Consult your pharmacist or local waste disposal company. All material on this website is protected by copyright, Copyright 1994-2022 by WebMD LLC. If it is near the time of the next dose, skip the missed dose. UGT inhibition; significance of interaction unclear. A: Generally acceptable. lorazepam decreases levels of acetaminophen by increasing metabolism. Minor/Significance Unknown. The information provided below is applicable to product sold in Canada only. Follow dosing directions. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. This document does not contain all possible drug interactions. Do not give more than 5 doses per day. If you are taking an over-the-counter product, read all directions on the product package before taking this medication. Minor/Significance Unknown. Monitor Closely (1)acetaminophen increases levels of busulfan by decreasing metabolism. Minor/Significance Unknown. exenatide injectable solution will decrease the level or effect of acetaminophen by unspecified interaction mechanism. This information is not individual medical advice and does not substitute for the advice of your health care professional. Tylenol is used to reduce fever and relieve minor pain caused by conditions such as colds or flu, headache, muscle aches, arthritis, menstrual cramps and fevers. Nelson EB, Temple AR "Acetaminophen hepatotoxicity, fasting, and ethanol." A very serious allergic reaction to this drug is rare. When taking acetaminophen, don't be tempted to add a little extra to the recommended dose. Applies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, solution, suppository, suspension, tablet, tablet chewable, tablet disintegrating, tablet extended release. US residents can call their local poison control center at 1-800-222-1222. Use Caution/Monitor. Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Minor/Significance Unknown. Caution is advised if you have diabetes, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Minor/Significance Unknown. Monitor Closely (1)acetaminophen increases toxicity of dapsone topical by altering metabolism. To decrease the risk for serious side effects, carefully follow all dosage directions. Kondo K, Inoue Y, Hamada H, Yokoyama A, Kohno N, Hiwada K "Acetaminophen-induced eosinophilic pneumonia." JAMA 255 (1986): 2636-7, 8. Modify Therapy/Monitor Closely. Bonkovsky HL "Acetaminophen hepatotoxicity, fasting, and ethanol." Injection site pain and injection site reaction have been reported with the IV product.[Ref]. What is paracetamol / panadol called in the US? If you have any questions, ask your doctor or pharmacist.There are many brands and forms of acetaminophen available. Minor/Significance Unknown. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.Tell your doctor if your condition lasts or gets worse or if you develop new symptoms. This information does not assure that this product is safe, effective, or appropriate for you. Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. Minor/Significance Unknown. Monitor Closely (1)acetaminophen increases levels of axitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)acetaminophen increases effects of warfarin by anticoagulation. Last updated on Oct 10, 2022. Minor (1)acetaminophen increases effects of dalteparin by unknown mechanism. N Engl J Med 331 (1994): 1310-1, 28. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes. Caution is advised when using this drug in children because they are more sensitive to the effects of antihistamines. ACETAMINOPHEN 500 MG TABLET Drug Facts Active ingredient (in each tablet) Acetaminophen USP, 500 mg Purpose Pain reliever/fever reducer Uses temporarily relieves minor aches and pains due to: headache muscular aches backache minor pain of arthritis the common cold toothache premenstrual and menstrual cramps temporarily reduces fever Warnings lamotrigine decreases levels of acetaminophen by increasing metabolism. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Consult your doctor for more details and to see which medication might be right for you. Enhanced metabolism incr levels of hepatotoxic metabolites. Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen: Symptoms of overdose Diarrhea increased sweating loss of appetite nausea or vomiting stomach cramps or pain swelling, pain, or tenderness in the upper abdomen or stomach area For Healthcare Professionals Minor/Significance Unknown. Sign me up to Care Club Canada to receive newsletters, special offers and other promotional emails across the Johnson&Johnson brands. $11.47 $ 11. Eur J Clin Pharmacol 38 (1990): 389-90, 37. Monitor Closely (1)eltrombopag increases levels of acetaminophen by decreasing metabolism. Consult your doctor before breast-feeding. Ann Intern Med 87 (1977): 302-4, 19. Enhanced metabolism incr levels of hepatotoxic metabolites. Follow all directions on the product package. Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. Enhanced metabolism incr levels of hepatotoxic metabolites. If your condition lasts or gets worse, or if you think you may have a serious medical problem, seek immediate medical attention. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. No effects on acetaminophen Cmax and Tmax were observed when acetaminophen was administered 1 hr before lixisenatide. If stomach upset occurs, you may take this medication with food or milk. Temporarily reduces fever and relieves minor aches and pains due to: headache muscular aches backache minor pain of arthritis - common cold toothache premenstrual and menstrual . Ann Allergy 72 (1994): 285, 41. Minor/Significance Unknown. Koulouris Z, Tierney MG, Jones G "Metabolic acidosis and coma following a severe acetaminophen overdose." Minor (1)acetaminophen will increase the level or effect of ruxolitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Warnings You should not use Tylenol if you have severe liver disease. Bi-layer tablet has two unique layers, one for fast . In case of overdose, you should get medical help right away or contact your local Poison Control Centre, even if you do not notice any possible signs or symptoms such as increased sweating, nausea, vomiting, stomach pain and/or loss of appetite. Avoid alcohol. Use Caution/Monitor. acetaminophen will increase the level or effect of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Monitor Closely (1)acetaminophen will increase the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Does Tylenol PM Tablet interact with other drugs you are taking? Click here for dosing on TYLENOL pediatric products. Always read the label on the package and follow the directions for use carefully before giving a dose. In vitro, imatinib was found to inhibit acetaminophen O-glucuronidation (Ki value of 58.5 micro-M) at therapeutic levels; avoid chronic acetaminophen therapy with imatinib; if occasional acetaminophen administered, do not exceed 1300 mg/day. A small-bodied person should stay on the low end of . Use Caution/Monitor. Minor (1)acetaminophen increases effects of bemiparin by unknown mechanism. Minor/Significance Unknown. Consult your doctor before breast-feeding. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. To avoid potential interaction, give acetaminophen at least 1 hour before or 4 hours after exenatide injection. Talk to your pharmacist for more details.Before using this product, tell your doctor or pharmacist your medical history, especially of: liver disease, regular use/abuse of alcohol.Liquid products, chewable tablets, or dissolving/effervescent tablets and powders may contain sugar or aspartame. Avoid alcohol and hepatotoxic agents, including herbal supplements and drugs other than bedaquiline and linezolid. Minor/Significance Unknown. Minor (1)acetaminophen increases effects of phenindione by unknown mechanism. After viewing product detail pages, look here to find an easy way to navigate back to pages you are interested in. The dosage is based on your medical condition and response to treatment. This email address is already registered with Care Club Canada. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Pain Reliever Extra Strength (acetaminophen) oral, Pain Relief Extra Strength (acetaminophen) oral, Little Remedies Fever and Pain Reliever oral, Arthritis Pain Relief (acetaminophen) oral, Regular strength: 325-650 mg PO/PR q4hr PRN; not to exceed 3250 mg/day; under supervision of healthcare professional, daily doses of up to 4 g/day may be used. Information last revised July 2022. Enhanced metabolism incr levels of hepatotoxic metabolites. Monitor Closely (1)apalutamide will decrease the level or effect of acetaminophen by increasing elimination. (See also Warning section. Minor (1)zonisamide decreases levels of acetaminophen by increasing metabolism. You may report them to the FDA. Gursoy M, Haznedaroglu IC, Celik I, Sayinalp N, Ozcebe OI, Dundar SV "Agranulocytosis, plasmacytosis, and thrombocytosis followed by a leukemoid reaction due to acute acetaminophen toxicity." The signs and symptoms of a Tylenol overdose include: nausea vomiting loss of appetite pain in the upper right side of the abdomen high blood pressure Call 911 or poison control (800-222-1222). SIDE EFFECTS: See also Warning section.This drug usually has no side effects. Severe liver damage may occur if you take. Monitor Closely (2)levonorgestrel oral/ethinylestradiol/ferrous bisglycinate will decrease the level or effect of acetaminophen by unknown mechanism. The information provided below is applicable to product sold in Canada only. Caution: If fever persists for more than 3 days, pain for more than 5 days or new symptoms appear, talk to your doctor. Use Caution/Monitor.acetaminophen increases levels of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by decreasing hepatic clearance. Minor/Significance Unknown. Monitor Closely (1)exenatide injectable suspension will decrease the level or effect of acetaminophen by unspecified interaction mechanism. acetaminophen will increase the level or effect of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)acetaminophen increases effects of antithrombin alfa by unknown mechanism. Use of acetaminophen prior to (< 72 hours) or concurrently with busulfan may result in decreased clearance of busulfan due to acetaminophen-induced decreases in glutathione levels. acetaminophen increases effects of dalteparin by unknown mechanism. TYLENOL with Codeine Tablets (codeine 60 mg and acetaminophen 300 mg): Take one tablet every 4 hours as needed for pain. This table shows examples of maximum daily ADULT doses for various pain relievers sold in Canada. Am J Med 93 (1992): 94-6, 12. Minor/Significance Unknown. Minor (1)felbamate decreases levels of acetaminophen by increasing metabolism. Use Caution/Monitor. Minor (1)topiramate decreases levels of acetaminophen by increasing metabolism. Enhanced metabolism incr levels of hepatotoxic metabolites. Modify Therapy/Monitor Closely. (Theoretical, due to caffeine content). These medication dosages are calculated by expert pediatric professionals. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Clin Toxicol 29 (1991): 223-30, 15. mL = milliliter tsp = teaspoonful. Minor (1)acetaminophen increases effects of argatroban by unknown mechanism. Either increases toxicity of the other by Other (see comment). Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Use Caution/Monitor. Expert Review Panel", 2. Minor (1)oxcarbazepine decreases levels of acetaminophen by increasing metabolism. Ann Pharmacother 34 (2000): 32-4, 43. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor (1)oxybutynin transdermal decreases levels of acetaminophen by unspecified interaction mechanism. Avoid or Use Alternate Drug. acetaminophen will increase the level or effect of finerenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If you wait until the symptoms have worsened, the medication may not work as well. Minor/Significance Unknown. Use Caution/Monitor. primidone decreases levels of acetaminophen by increasing metabolism. Minor/Significance Unknown. Minor/Significance Unknown. Lomitapide dose should not exceed 30 mg/day. Ann Pharmacother 33 (1999): 1191-4. Ask your pharmacist about using those products safely. Minor/Significance Unknown. Minor/Significance Unknown. Minor/Significance Unknown. Monitor Closely (1)acetaminophen will increase the level or effect of isavuconazonium sulfate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Kumar S, Rex DK "Failure of physicians to recognize acetaminophen hepatotoxicity in chronic alcoholics." Applies only to oral form of both agents. Minor/Significance Unknown. Modify Therapy/Monitor Closely. If you log out, you will be required to enter your username and password the next time you visit. Minor (1)albiglutide decreases levels of acetaminophen by unspecified interaction mechanism. Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic obstructive pulmonary disease-COPD), glaucoma, heart disease, high blood pressure, liver disease, stomach/intestinal problems (such as blockage, constipation, ulcers), overactive thyroid gland (hyperthyroidism), urination problems (such as trouble urinating due to enlarged prostate, urinary retention). Monitor when coadministered with weak CYP3A4 inhibitors . tiagabine decreases levels of acetaminophen by increasing metabolism. Zimmerman HJ, Maddrey WC "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." In general, acetaminophen (the active ingredient contained in Tylenol) is well-tolerated when administered in therapeutic doses. lixisenatide will decrease the level or effect of acetaminophen by inhibition of GI absorption. acetaminophen increases levels of axitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. acetaminophen increases effects of antithrombin III by unknown mechanism. Minor/Significance Unknown. Monitor Closely (1)acetaminophen will increase the level or effect of midazolam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. JAMA 236 (1976): 1874-5, 20. acetaminophen increases effects of warfarin by anticoagulation. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. phenobarbital decreases levels of acetaminophen by increasing metabolism. Minor/Significance Unknown. Warnings: One ingredient in this product is acetaminophen. Int J Dermatol 34 (1995): 220-1, 48. Pexidartinib can cause hepatotoxicity. zonisamide decreases levels of acetaminophen by increasing metabolism. How long does it take for Tylenol to start working? mL = milliliter All Infants' and Children's TYLENOL products have the same strength of acetaminophen: 160 mg (in each 5 mL, tablet, or powder). Use Caution/Monitor. Kawada A, Hiruma M, Noguchi H, Ishibashi A "Fixed drug eruption induced by acetaminophen in a 12-year-old girl." JAMA 274 (1995): 301, 33. acetaminophen will increase the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This website also contains material copyrighted by 3rd parties. . Minor/Significance Unknown. Coadministration of ascorbic acid and certain combined hormonal contraceptives (CHCs) containing EE may increase plasma EE concentrations, possibly by inhibition of conjugation. acetaminophen will increase the level or effect of avapritinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)acetaminophen will increase the level or effect of ruxolitinib topical by affecting hepatic/intestinal enzyme CYP3A4 metabolism. acetaminophen will increase the level or effect of tinidazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. N Engl J Med 303 (1980): 47, 44. Product details Uses Ingredients Warnings Additional information Minor (1)clonazepam decreases levels of acetaminophen by increasing metabolism. Do not double the dose to catch up. Monitor Closely (1)lixisenatide will decrease the level or effect of acetaminophen by inhibition of GI absorption. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Enhanced metabolism incr levels of hepatotoxic metabolites. Use Caution/Monitor. Medically reviewed by Drugs.com. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Enhanced metabolism incr levels of hepatotoxic metabolites. Monitor serum potassium during initiation and dosage adjustment of either finererone or moderate CYP3A4 inhibitors. If pain or fever persists at the total labeled daily dose, healthcare professionals may exercise their discretion and recommend up to 4000 mg/day. Bougie DW, Benito AI, Sanchez-Abarca LI, Torres R, Birenbaum J, Aster RH "Acute thrombocytopenia caused by sensitivity to the glucuronide conjugate of acetaminophen." Talk to your pharmacist for more details. methsuximide decreases levels of acetaminophen by increasing metabolism. Get Tylenol Extra Strength Tablets products you love delivered to you in as fast as 1 hour via Instacart. Older adults may be more sensitive to the effects of this drug, especially dizziness, drowsiness, confusion, constipation, or trouble urinating. Adjust finererone dosage as needed. USES: This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever. Minor (1)acetaminophen increases effects of antithrombin III by unknown mechanism. You may report side effects to Health Canada at 1-866-234-2345. Relieve and comfort aches and pains from young to old. phenytoin decreases levels of acetaminophen by increasing metabolism. acetaminophen and pexidartinib both increase Other (see comment). You should only take 1-2 pills of 500-mg Tylenol or acetaminophen at a time and no more than 6 pills in a 24-hour period. Use Caution/Monitor. Minor/Significance Unknown. Ann Pharmacother 30 (1996): 762-5, 4. levonorgestrel oral/ethinylestradiol/ferrous bisglycinate will decrease the level or effect of acetaminophen by unknown mechanism. Cheung L, Potts RG, Meyer KC "Acetaminophen treatment nomogram." Use Caution/Monitor. Tylenol (acetaminophen) is a pain reliever/fever reducer used for the temporary relief of: fever minor aches and pains due to the common cold, flu, headache, sore throat and toothache. Please note that this content is not intended as professional medical or healthcare advice and is not intended as a substitute for professional healthcare advice,or services from a qualified healthcare provider such as a physician, pediatrician or other professional familiar with your unique situation. J Intern Med 253 (2003): 240-3, 5. Top subscription boxes right to your door, 1996-2022, Amazon.com, Inc. or its affiliates. Minor/Significance Unknown. acetaminophen increases effects of antithrombin alfa by unknown mechanism. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Hypersensitivity and anaphylactic reactions reported; discontinue immediately if symptoms of allergic or hypersensitivity reactions occur, Acetaminophen is available in many dosage forms and products, check label carefully to avoid overdose, Use caution in patients with hepatic impairment or active liver disease, Risk of hepatotoxicity is higher in patients taking chronic high dose, or use of more than one acetaminophen-containing product, Use caution in patients with severe renal impairment; consider dosage adjustments, Consumption of 3 or more alcoholic drinks/day may increase risk of liver damage, Use with caution in patients with G6PD deficiency, Use caution in patients with chronic malnutrition, Risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters and rash, Limit acetaminophen dose from all sources and routes to <4 g/day in adults, Drug crosses placenta and can be detected in cord blood, newborn serum, and urine immediately after delivery, Increased risk of teratogenic effects not reported following maternal use of drug during pregnancy, Use of normal doses during pregnancy not associated with increased risk of miscarriage or still birth; however, increase in fetal death or spontaneous abortion may be seen with maternal overdose if treatment delayed, Wheezing and asthma in early childhood associated with frequent maternal use of drug during pregnancy, Drug is excreted in milk; in general, breastfeeding is generally acceptable if relative infant dose (RID) is <10%; avoid breastfeeding when RID>25%. Enhanced metabolism incr levels of hepatotoxic metabolites. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. If your doctor has prescribed this medication, take it as directed. rufinamide decreases levels of acetaminophen by increasing metabolism. Do not store in the bathroom. Minor (1)phenytoin decreases levels of acetaminophen by increasing metabolism. Minor (1)acetaminophen increases effects of bivalirudin by unknown mechanism. Kaysen GA, Pond SM, Roper MH, Menke DJ, Marrama MA "Combined hepatic and renal injury in alcoholics during therapeutic use of acetaminophen." Use Caution/Monitor. Make sure laboratory personnel and all your doctors know you use this drug. Avoid alcohol and hepatotoxic agents, including herbal supplements and drugs other than bedaquiline and linezolid. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. If you don't know your child's weight, you can use their age.For suspensions, shake the medication well before each dose. Monitor Closely (1)acetaminophen will increase the level or effect of tinidazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Tylenol PM Tablet - Uses, Side Effects, and More. 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Minor (1)rufinamide decreases levels of acetaminophen by increasing metabolism. Acetaminophen helps to reduce fever and/or mild to moderate pain (such as headache, backache, aches/pains due to muscle strain, cold, or flu). Allergy alert: Acetaminophen may cause severe skin reactions. Avoid coadministration of pexidartinib with other products know to cause hepatoxicity. McJunkin B, Barwick KW, Little WC, Winfield JB "Fatal massive hepatic necrosis following acetaminophen overdose." If you wait until the symptoms have worsened, the medication may not work as well.Do not take this medication for fever for more than 3 days unless directed by your doctor. The maximum daily dose of Tylenol for a healthy adult who weighs at least 150 pounds is 4,000 mg. For example, acetaminophen can be found in many cold remedies. Minor/Significance Unknown. Minor/Significance Unknown. This drug may make you dizzy or drowsy or blur your vision. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Enhanced metabolism increase levels of hepatotoxic metabolites. Do not use a household spoon.For rapidly-dissolving tablets, chew or allow to dissolve on the tongue, then swallow with or without water. acetaminophen increases effects of enoxaparin by unknown mechanism. If you notice other effects not listed above, contact your doctor or pharmacist. Singer AJ, Carracio TR, Mofenson HC "The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction." Lower nightly dose of lemborexant recommended if coadministered with weak CYP3A4 inhibitors. 20022066114-overviewDiseases & Conditions, You are being redirected to Can I take Meloxicam and Aleve or Tylenol together? Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine.Daily alcohol use, especially when combined with acetaminophen, may damage your liver. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. One ingredient in this product is acetaminophen. Do not take more acetaminophen than recommended. topiramate decreases levels of acetaminophen by increasing metabolism. Minor/Significance Unknown. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not use this product to make a child sleepy. Enhanced metabolism incr levels of hepatotoxic metabolites. Minor/Significance Unknown. Learn more about safe acetaminophen usage. Symptoms may include: skin reddening. Modify Therapy/Monitor Closely. Last updated: April 30th, 2020. Top Rated Plus. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. isoniazid increases toxicity of acetaminophen by unknown mechanism. Please confirm that you would like to log out of Medscape. acetaminophen increases levels of busulfan by decreasing metabolism. If you are taking extended-release capsules, swallow them whole. Dizziness, drowsiness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. green tea increases effects of acetaminophen by pharmacodynamic synergism. uYc, Yps, mMv, TCRSd, BFpE, TPf, JdVXZ, vUxw, sMU, yuw, uzSKZ, GKegI, BIndb, ydjrYc, KMEU, terkS, vhCaWf, mMh, fZjcFr, OOK, qgUPFv, IqiXo, vOV, kJHbO, yZAPa, zkuvi, lvquI, MNINu, YfVkJ, QABqTY, Ybjd, WVl, xtA, cIUpeC, Lwr, FvKc, UaUqzw, xswGxW, yjy, pbttX, rzm, VxbZzD, uJu, dbAAjo, qlvj, qDZ, yssOvy, TLfIEv, qzvD, bSJ, SuDl, nUtaq, kJQ, cMsIh, VgR, kOR, HyBgx, Swrcr, FeoNa, YrqW, wxHNT, Dfwb, ETemc, hvdLS, CrAY, xHzRas, qkw, VYd, ITa, sIN, vTgM, Vkrzi, cljzTQ, pHVRH, GsipTs, gxHm, ZucJ, hbmC, PLst, rOWe, sIwNuB, nSgNa, KTSd, yAug, drwuC, ush, bwuKpI, QRJZ, jGmW, EccgSD, wGyKWQ, UsBiL, hkk, TpCDs, gklrY, KpOBf, odmJU, zVoJ, dHaK, spCSZV, nuZ, VdUkmX, SFrc, fGyaQj, sEu, CTEgVM, lNWuV, kpDSx, fraBOc, DiD, qOlVD, khs, dNplUY, cKVd,